The safest method to ensure a burger is cooked to a food-safe temperature is to use an instant-read thermometer. The USDA recommends ground beef be cooked to 160°F (71°C) to destroy harmful bacteria. Insert the thermometer into the side of the patty into the center for an accurate reading.
If you don’t have a thermometer, use visual and timing cues: a fully cooked all-beef patty will have no pink in the center and clear juices, and the exterior will be well-browned. However, these methods are less reliable since color can vary, so a thermometer is the best tool.
Using an instant-read thermometer is the most reliable and safest approach to ensure burgers reach the recommended internal temperature while staying as juicy as possible.